Document Detail


Viral etiology of pneumonia in a cohort of newborns till 24 months of age in Rural Mirzapur, Bangladesh.
MedLine Citation:
PMID:  16857616     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Limited information is available on the etiology of acute lower respiratory infection (ALRI) particularly pneumonia in the rural community of developing countries since most etiological studies are carried out in the hospital settings. This study examined the etiology of pneumonia among young children in a rural community of Bangladesh. A cohort of 252 newborns was followed till 24 months of age during 1993-1996. Community health workers (CHWs) identified cases of ALRI during household surveillance and recommended hospitalization. On admission, nasopharyngeal aspirates (NPA) and blood were collected for bacterial and viral identification, and chest x-rays were done. Multiple regression analysis identified factors associated with a viral etiology. Physicians diagnosed 67 pneumonia; 45% of NPA were positive for viral agents of pneumonia, and respiratory syncytial virus (RSV) was predominant (81%); 6 of 48 blood cultures were positive. X-ray was done for 58 cases; 52% had pneumonic consolidation. Of the RSV cases, 33% were found in children without pneumonic consolidation. Children living in a one-room house were 3 times more likely to develop viral pneumonia (odds ratio (OR) = 3.67, CI 1.05-12.83) than children living in a larger house. Counseling on avoiding crowding where a newborn is accommodated might reduce pneumonia incidence.
Authors:
Khundkar Hasan; Pauline Jolly; Grace Marquis; Eliza Roy; Goutam Podder; Khorshed Alam; Fazlul Huq; Richard Sack
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Scandinavian journal of infectious diseases     Volume:  38     ISSN:  0036-5548     ISO Abbreviation:  Scand. J. Infect. Dis.     Publication Date:  2006  
Date Detail:
Created Date:  2006-07-21     Completed Date:  2006-10-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0215333     Medline TA:  Scand J Infect Dis     Country:  Sweden    
Other Details:
Languages:  eng     Pagination:  690-5     Citation Subset:  IM    
Affiliation:
ICDDR,B: Centre for Health and Population Research, Dhaka, Bangladesh. Zahid@icddrb.org
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MeSH Terms
Descriptor/Qualifier:
Bangladesh / epidemiology
Child, Preschool
Cohort Studies
Humans
Infant
Infant, Newborn
Infant, Newborn, Diseases / epidemiology,  virology*
Influenza B virus / isolation & purification
Logistic Models
Parainfluenza Virus 2, Human / isolation & purification
Parainfluenza Virus 3, Human / isolation & purification
Pneumonia, Viral / epidemiology,  microbiology,  virology*
Respiratory Syncytial Viruses / isolation & purification

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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