Document Detail


Vincristine treatment of nephrotic syndrome complicated by Kimura disease.
MedLine Citation:
PMID:  15690191     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Kimura disease is a rare inflammatory condition of unknown aetiology. It typically presents in young Asian males with the triad of non-tender subcutaneous swellings in the head and neck region, peripheral eosinophilia and raised serum IgE. About 16% of cases have associated renal disease. We present the case of a 10-year-old boy with a past history of steroid responsive, frequently relapsing nephrotic syndrome who developed a right submandibular swelling and eosinophilia. Kimura disease was diagnosed on the basis of clinical and histological findings. The condition recurred during relapses of nephrotic syndrome. Because of poor adherence with oral medication, our patient was treated with intravenous vincristine with synchronous remissions of his nephrotic syndrome and Kimura swellings on each occasion.
Authors:
Annette Connelly; Harley R Powell; Yuen F Chan; David Fuller; Russell G Taylor
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-02-03
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  20     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-03-04     Completed Date:  2005-06-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  516-8     Citation Subset:  IM    
Affiliation:
Department of Nephrology, Royal Children's Hospital, Parkville 3052, Melbourne, Victoria, Australia.
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MeSH Terms
Descriptor/Qualifier:
Angiolymphoid Hyperplasia with Eosinophilia / complications*,  drug therapy*,  pathology
Child
Humans
Injections, Intravenous
Male
Nephrotic Syndrome / complications*,  drug therapy*
Recurrence
Remission Induction
Vincristine / administration & dosage,  therapeutic use*
Chemical
Reg. No./Substance:
57-22-7/Vincristine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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