Document Detail


Villoglandular adenocarcinoma of the cervix: clarity is needed on the histological definition for this difficult diagnosis.
MedLine Citation:
PMID:  16266744     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Villoglandular adenocarcinoma (VGA) of the cervix is reported as a variant of a cervical adenocarcinoma with a good prognosis. CASES: We present two cases histologically reported as a villoglandular adenocarcinoma of the cervix that have recurred and progressed rapidly since initial treatment. External histopathological review suggested both had a prominent villoglandular pattern but with an associated underlying well-differentiated adenocarcinoma. CONCLUSION: The diagnosis of VGA is difficult. Current literature is not entirely consistent in the presented definition, and further clarity is needed. Because of the rarity of VGA and the difficulty but importance of the diagnosis, we would feel that a central review of all cases of VGA is warranted. This would assist in diagnosis and also in obtaining accurate follow-up data.
Authors:
R D Macdonald; J Kirwan; K Hayat; C S Herrington; H Shawki
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-11-02
Journal Detail:
Title:  Gynecologic oncology     Volume:  100     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-21     Completed Date:  2006-02-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  192-4     Citation Subset:  IM    
Affiliation:
Department of Gynaecological Oncology, Liverpool Womens Hospital, Liverpool L8 7SS, UK. Robert.macdonald@lwh.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / diagnosis,  pathology*
Adult
Female
Humans
Neoplasm Recurrence, Local / diagnosis,  pathology
Uterine Cervical Neoplasms / diagnosis,  pathology*

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