Document Detail


Videocinematography of fresh and cryopreserved embryos: a retrospective analysis of embryonic morphology and implantation.
MedLine Citation:
PMID:  2707457     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eleven morphologic criteria were studied from videotapes of 323 fresh and 103 thawed embryos. The proportion of thawed embryos (30/39; 77%) with more than one abnormality was (P = 0.03) higher than that of fresh embryos (5/13; 38%), despite similar implantation rates (18% and 15%, respectively). The best predictor of thawed embryo implantation was cell-cell adherence: when scored "positive," 11 of 17 women (65%) became pregnant, whereas none became pregnant (0/15; P = 0.0002) when blastomeres did not adhere. The total number of abnormalities for thawed embryos was an important prognostic. An increased percentage variation of zona pellucida thickness was the most important prognostic for fresh embryos. When the "best" embryo had a zona pellucida that varied more than 25%, 24 of 60 (40%) resulted in pregnancy; pregnancies were not induced (0/21) when the "best" embryo had less than 10% variation (P = 0.0003).
Authors:
J Cohen; K L Inge; M Suzman; S R Wiker; G Wright
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  51     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-06-07     Completed Date:  1989-06-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  820-7     Citation Subset:  IM    
Affiliation:
Reproductive Biology Associates, Atlanta, Georgia.
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MeSH Terms
Descriptor/Qualifier:
Blastomeres / ultrastructure
Embryo Transfer*
Embryo, Mammalian / ultrastructure*
Freezing*
Humans
Retrospective Studies
Semen Preservation
Videotape Recording*
Zona Pellucida / ultrastructure
Comments/Corrections
Comment In:
Fertil Steril. 1989 Nov;52(5):877-8   [PMID:  2806627 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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