| Videocapillaroscopy in postburn scars: in vivo analysis of the microcirculation. | |
| | |
MedLine Citation:
|
PMID: 20381256 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
OBJECTIVE: The aim of the study was the evaluation in vivo of the differences between the microcirculatory characteristics of the postburn scar and the healthy skin. METHODS: Twelve patients with postburn scars were included in the study, evaluating fifteen scar areas and twelve healthy skin areas by means of contact optical probe videocapillaroscopy. The examined areas for each patient were the right and the left upper limb. Capillary density, length and diameter, together with capillary distribution pattern (punctiform, reticular, directional) and the presence of microhaemorrhages and neoangiogenesis were studied. RESULTS: The results were obtained by two different researchers using the capillaroscope's software. Capillary loop diameter and length, capillary distribution pattern and presence of neoangiogenesis were found to be significantly increased in postburn scars compared with controls. There were also significant differences between hypertrophic tissue in the active phase and the one in the remission phase for capillary diameter and presence of neoangiogenesis. CONCLUSION: Videocapillaroscopy showed "in vivo" a change in local microcirculation architecture using a microscope. Patients with hypertrophic burn scars showed a variety of microcirculatory changes, often clustered in a characteristic pattern of abnormally oriented, dilated capillaries and neoangiogenetic phenomena. This methodology is highly likely to be of value in the assessment and prognostication of burn outcome. |
| | |
Authors:
|
Ezio Nicola Gangemi; Riccardo Carnino; Maurizio Stella |
Related Documents
:
|
2919846 - Changes in oxygenation and pulse rate during endoscopy. 19775036 - Non-invasive assessment of the microcirculation in critically ill patients. 17727266 - Single breath tracing for carbon dioxide in septic patients with tissue hypoxia. 697436 - Opsonic alpha2 surface binding glycoprotein therapy during sepsis. 12589836 - Bk virus (bkv) quantification in urine samples of bone marrow transplanted patients is ... 9129736 - Chromosome instability with bleomycin and x-ray hypersensitivity in a boy with nijmegen... |
Publication Detail:
|
Type: Journal Article Date: 2010-04-08 |
Journal Detail:
|
Title: Burns : journal of the International Society for Burn Injuries Volume: 36 ISSN: 1879-1409 ISO Abbreviation: Burns Publication Date: 2010 Sep |
Date Detail:
|
Created Date: 2010-07-30 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8913178 Medline TA: Burns Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 799-805 Citation Subset: IM |
Copyright Information:
|
2010 Elsevier Ltd and ISBI. All rights reserved. |
Affiliation:
|
Department of Plastic and Reconstructive Surgery, Burn Center, Traumatological Hospital, Turin, Italy. ezio.nicola@tele2.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Muscle contractile properties in severely burned rats.
Next Document: Pathway genetic load allows simultaneous evaluation of multiple genetic associations.