Document Detail

Video analysis of sensory-motor features in infants with fragile X syndrome at 9-12 months of age.
MedLine Citation:
PMID:  16172809     Owner:  NLM     Status:  MEDLINE    
This study utilized retrospective video analysis to distinguish sensory-motor patterns in infants with fragile X syndrome (FXS) (n = 11) from other infants [i.e., autism (n = 11), other developmental delay (n = 10), typical (n = 11)] at 9-12 months of age. Measures of development, autistic features, and FMRP were assessed at the time of entry into the study. Home videos collected from families were edited and coded with previously validated procedures. Findings revealed a pattern of sensory-motor features (e.g., repetitive leg movements, posturing, less sophistication/repetitive use of objects) associated with FXS, and suggest these infants were most similar to the group of infants with other developmental delays, irrespective of co-existing autistic symptoms later in life. Infant sensory-motor features in the FXS group were more predictive of an early developmental milestone (i.e., age walking) than later, more broad, developmental outcomes, or FMRP. Implications for early identification and differential diagnosis are discussed.
Grace T Baranek; Cassandra D Danko; Martie L Skinner; Donald B Bailey; Donald B Jr; Deborah D Hatton; Jane E Roberts; Penny L Mirrett
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of autism and developmental disorders     Volume:  35     ISSN:  0162-3257     ISO Abbreviation:  J Autism Dev Disord     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2006-02-22     Completed Date:  2006-03-21     Revised Date:  2012-01-30    
Medline Journal Info:
Nlm Unique ID:  7904301     Medline TA:  J Autism Dev Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  645-56     Citation Subset:  IM    
Division of Occupational Science, Department of Allied Health Sciences, University of North Carolina at Chapel Hill, NC 27599-7120, USA.
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MeSH Terms
Fragile X Syndrome / epidemiology*
Intellectual Disability / epidemiology
Psychomotor Disorders / diagnosis,  epidemiology*
Severity of Illness Index
Stereotypic Movement Disorder / diagnosis,  epidemiology
Videotape Recording*
Erratum In:
J Autism Dev Disord. 2012 Jan;42(1):94
Note: Jr, Donald B [corrected to Bailey, Donald B Jr]

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