| Video-assisted thoracic surgery lobectomy for non-small cell lung cancer in patients with a Charlson comorbidity index score of two or more. | |
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MedLine Citation:
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PMID: 19875973 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: We evaluated the feasibility and safety of the video-assisted thoracic surgery (VATS) lobectomy for non-small cell lung cancer (NSCLC) in patients with comorbidity. METHODS: Between April 2000 and December 2006, a prospective database of 58 consecutive patients undergoing a VATS lobectomy for NSCLC, who had a Charlson comorbidity index score of 2 or more, was retrospectively analyzed. The demographic, perioperative, histopathologic, and outcome variables, including the recurrence and survival, were assessed. RESULTS: The VATS lobectomy was successfully performed in 57 patients (16 women and 41 men; median age, 70 years). Twenty-three patients (40.4%) were aged 75 years or older. The total score of the Charlson comorbidity index was as follows: 2 in 26 patients, 3 in 13 patients, 4 in 12 patients, 5 in five patients, and 6 in one patient. None of the patients required a blood transfusion during surgery or during the postoperative course. We observed no intraoperative or in-hospital deaths, and no complications occurred in the 45 patients (78.9%). At a median follow-up of 34 months, a recurrence was observed in five patients who had advanced stages: a local recurrence in one and a distant recurrence in four. The overall 5-year survival rates for postoperative stage IA (n = 25) and IB (n = 16) were 100% and 94%, respectively. CONCLUSIONS: We believe that a VATS lobectomy is a feasible and safe procedure for NSCLC in patients with comorbidity because this modality demonstrates an acceptable morbidity and a favorable oncologic outcome. |
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Authors:
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Ryoichi Nakanishi; Toshihiro Yamashita; Soichi Oka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer Volume: 5 ISSN: 1556-1380 ISO Abbreviation: J Thorac Oncol Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-25 Completed Date: 2010-03-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101274235 Medline TA: J Thorac Oncol Country: United States |
Other Details:
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Languages: eng Pagination: 56-61 Citation Subset: IM |
Affiliation:
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Department of Thoracic Surgery, Shin-Kokura Hospital, Federation of National Public Service Personnel Mutual Aid Associations, Kokurakita-ku, Kitakyushu, Japan. ryoichi@med.uoeh-u.ac.jp |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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secondary,
surgery* Adenocarcinoma, Bronchiolo-Alveolar / secondary, surgery* Aged Aged, 80 and over Carcinoma, Non-Small-Cell Lung / secondary, surgery* Carcinoma, Squamous Cell / secondary, surgery* Comorbidity Feasibility Studies Female Follow-Up Studies Humans Lung Neoplasms / pathology, surgery* Male Middle Aged Neoplasm Staging Pneumonectomy* Prognosis Prospective Studies Retrospective Studies Survival Rate Thoracic Surgery, Video-Assisted / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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