| Vibrational spectroscopic study of fluticasone propionate. | |
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MedLine Citation:
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PMID: 19095495 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fluticasone propionate is a synthetic glucocorticoid with potent anti-inflammatory activity that has been used effectively in the treatment of chronic asthma. The present work reports a vibrational spectroscopic study of fluticasone propionate and gives proposed molecular assignments on the basis of ab initio calculations using BLYP density functional theory with a 6-31G* basis set and vibrational frequencies predicted within the quasi-harmonic approximation. Several spectral features and band intensities are explained. This study generated a library of information that can be employed to aid the process monitoring of fluticasone propionate. |
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Authors:
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H R H Ali; H G M Edwards; J Kendrick; I J Scowen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-11-05 |
Journal Detail:
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Title: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Volume: 72 ISSN: 1386-1425 ISO Abbreviation: Spectrochim Acta A Mol Biomol Spectrosc Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-01-12 Completed Date: 2009-03-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9602533 Medline TA: Spectrochim Acta A Mol Biomol Spectrosc Country: England |
Other Details:
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Languages: eng Pagination: 244-7 Citation Subset: IM |
Affiliation:
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School of Life Sciences, University of Bradford, Bradford, BD7 1DP, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Androstadienes
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chemistry* Anti-Inflammatory Agents / chemistry* Molecular Structure Spectrum Analysis, Raman* Vibration |
| Chemical | |
Reg. No./Substance:
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0/Androstadienes; 0/Anti-Inflammatory Agents; 90566-53-3/fluticasone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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