Document Detail


Vibrating perception threshold and body mass index are associated with abnormal foot plantar pressure in type 2 diabetes outpatients.
MedLine Citation:
PMID:  22934798     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: This study investigated the influencing factors of foot plantar pressure and attempted to find practical indicators to predict abnormal foot pressure in patients with type 2 diabetes mellitus (T2DM).
SUBJECTS AND METHODS: Vibration perception threshold (VPT) and foot plantar pressure in 1,126 T2DM outpatients were examined. Patients were assigned to Group A (n=599), Group B (n=312), and Group C (n=215) according to VPT values and to Group I (n=555), Group II (n=436), and Group III (n=135) based on body mass index (BMI). The clinical characteristics and pressure-time integral (PTI) were compared among the three groups, and the associated factors of the total PTI in the entire foot (T-PTI) were analyzed.
RESULTS: PTI of Group C in heel medial and heel lateral was significantly higher than that of Group A (all P<0.01). PTI of Group B in the right fifth metatarsal and heel medial was significantly higher than that of Group A (all P<0.05). T-PTI of Group C was significantly higher than those of Groups A and B, and that of Group B was higher than that of Group A (all P<0.01). PTI of Groups II and III in the second, third, and fourth metatarsal, midfoot, heel medial, and heel lateral was significantly higher than that of Group I (all P<0.05). T-PTI of Groups II and III was significantly higher than that of Group I (all P<0.01). Pearson correlation analysis showed that T-PTI was positively associated with age, VPT, waist circumference, waist-to-hip ratio, and BMI (P<0.05). In multiple stepwise regression analysis, VPT (P=0.004) and BMI (P=0.000) were independent risk factors of T-PTI, and each 1 unit increase in BMI increased the T-PTI by 5.962 kPa•s. Receiver operator characteristic curve analysis further revealed that the optimal cutpoint of VPT and BMI to predict the abnormal PTI was 21 V (odds ratio=2.33, 95% confidence interval 1.67-3.25) and 24.9 kg/m(2) (odds ratio=2.12, 95% confidence interval 1.55-2.90), respectively.
CONCLUSIONS: Having a VPT higher than 21 V and a BMI above 24.9 kg/m(2) increases the risk of excessive foot plantar pressure in Chinese T2DM.
Authors:
Jing Shen; Fang Liu; Hui Zeng; Jue Wang; Jun-Gong Zhao; Jun Zhao; Feng-Di Lu; Wei-Ping Jia
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-08-30
Journal Detail:
Title:  Diabetes technology & therapeutics     Volume:  14     ISSN:  1557-8593     ISO Abbreviation:  Diabetes Technol. Ther.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-29     Completed Date:  2013-04-02     Revised Date:  2013-11-05    
Medline Journal Info:
Nlm Unique ID:  100889084     Medline TA:  Diabetes Technol Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1053-9     Citation Subset:  IM    
Affiliation:
Department of Endocrinology & Metabolism, Shanghai Jiaotong University-Affiliated Sixth People's Hospital, Shanghai Clinical Medical Center of Diabetes, Shanghai Institute for Diabetes, Shanghai Key Laboratory of Diabetes, Shanghai, China.
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MeSH Terms
Descriptor/Qualifier:
Aged
Asian Continental Ancestry Group*
Body Mass Index
Diabetes Mellitus, Type 2 / epidemiology,  physiopathology*
Diabetic Foot / epidemiology,  physiopathology*,  prevention & control
Female
Forefoot, Human / physiopathology*
Humans
Male
Mass Screening
Middle Aged
Overweight / complications*,  epidemiology,  physiopathology
Perception
Pressure
Risk Factors
Risk Reduction Behavior
Vibration*
Waist-Hip Ratio
Weight Loss
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