| The vexing problem of guidelines and conflict of interest: a potential solution. | |
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MedLine Citation:
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PMID: 20479011 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Issues of financial and intellectual conflict of interest in clinical practice guidelines have raised increasing concern. Professional organizations have responded by more rigorous regulation of conflict of interest. Nevertheless, tension remains between the competing goals of optimizing guideline quality by using the experience and insight of experts and ensuring that financial and intellectual conflicts of interest do not influence recommendations. The executive committee of the American College of Chest Physicians' Antithrombotic Guidelines has developed a strategy comprising 3 innovative aspects to address this tension: First, place equal emphasis on intellectual and financial conflicts and provide explicit criteria for both; second, a methodologist without important conflicts of interest should have primary responsibility for each chapter; and third, experts with important financial or intellectual conflicts of interest can collect and interpret evidence, but only panel members without important conflicts can be involved in developing the recommendation for a specific question. These strategies may help to achieve the benefits of expert input without conflicts of interest influencing recommendations. |
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Authors:
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Gordon Guyatt; Elie A Akl; Jack Hirsh; Clive Kearon; Mark Crowther; David Gutterman; Sandra Zelman Lewis; Ian Nathanson; Roman Jaeschke; Holger Schünemann |
Publication Detail:
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Type: Journal Article Date: 2010-05-17 |
Journal Detail:
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Title: Annals of internal medicine Volume: 152 ISSN: 1539-3704 ISO Abbreviation: Ann. Intern. Med. Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-06-01 Completed Date: 2010-06-14 Revised Date: 2010-09-27 |
Medline Journal Info:
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Nlm Unique ID: 0372351 Medline TA: Ann Intern Med Country: United States |
Other Details:
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Languages: eng Pagination: 738-41 Citation Subset: AIM; IM |
Affiliation:
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McMaster University Health Sciences Centre, Henderson General Hospital, Hamilton, Ontario, Canada. guyatt@mcmaster |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Conflict of Interest*
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economics Consultants Disclosure Documentation Humans Practice Guidelines as Topic / standards* |
| Comments/Corrections | |
Comment In:
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Ann Intern Med. 2010 Sep 21;153(6):421; author repy 422
[PMID:
20855815
]
Ann Intern Med. 2010 Sep 21;153(6):421-2; author reply 422 [PMID: 20855814 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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