Document Detail


Vestibular perceptual thresholds to angular rotation in acute unilateral vestibular paresis and with galvanic stimulation.
MedLine Citation:
PMID:  21951002     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Studies of compensation of injury to the human vestibular system have, in the main, focused on the vestibular-ocular reflex. Probing vestibular perception allows more of the sensory pathway to be assessed. We present a novel paradigm for simultaneously testing vestibular perceptual and nystagmic thresholds to angular acceleration around an earth vertical axis. The perceptual thresholds can be modulated asymmetrically in normal subjects by DC galvanic stimulation with the head flexed in the roll plane, as expected from the main torsional plane of action of the galvanic stimulus. The perceptual and nystagmic thresholds were bilaterally elevated in acute vestibular neuritis, a unilateral condition, possibly due to central suppression of vestibular input. The degree of asymmetry in thresholds was small in comparison with the large caloric asymmetry present in the patients, indicating a relatively preserved capacity for near-threshold performance of the non-damaged labyrinth both in the "on" and "off" directions.
Authors:
Nicholas J Cutfield; Sian Cousins; Barry M Seemungal; Michael A Gresty; Adolfo M Bronstein
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  1233     ISSN:  1749-6632     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-09-28     Completed Date:  2011-11-30     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  256-62     Citation Subset:  IM    
Copyright Information:
© 2011 New York Academy of Sciences.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Case-Control Studies
Female
Humans
Male
Middle Aged
Nystagmus, Pathologic / physiopathology
Paresis / physiopathology*
Rotation
Sensory Thresholds / physiology*
Vestibular Neuronitis / diagnosis,  physiopathology*
Vestibule, Labyrinth / physiopathology*
Visual Perception / physiology
Young Adult
Grant Support
ID/Acronym/Agency:
G0600183//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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