Document Detail

Vestibular migraine: clinical aspects and pathophysiology.
MedLine Citation:
PMID:  23769597     Owner:  NLM     Status:  MEDLINE    
Vestibular migraine is becoming recognised as a distinct clinical entity that accounts for a high proportion of patients with vestibular symptoms. A temporal overlap between vestibular symptoms, such as vertigo and head-movement intolerance, and migraine symptoms, such as headache, photophobia, and phonophobia, is a requisite diagnostic criterion. Physical examination and laboratory testing are usually normal in vestibular migraine but can be used to rule out other vestibular disorders with overlapping symptoms. The pathophysiology of vestibular migraine is incompletely understood but plausibly could include neuroanatomical pathways to and from central vestibular structures and neurochemical modulation via the locus coeruleus and raphe nuclei. In the absence of controlled trials, treatment options for patients with vestibular migraine largely mirror those for migraine headache.
Joseph M Furman; Dawn A Marcus; Carey D Balaban
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Lancet. Neurology     Volume:  12     ISSN:  1474-4465     ISO Abbreviation:  Lancet Neurol     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-17     Completed Date:  2013-08-23     Revised Date:  2014-08-15    
Medline Journal Info:
Nlm Unique ID:  101139309     Medline TA:  Lancet Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  706-15     Citation Subset:  IM    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
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MeSH Terms
Calcium Channels / genetics,  physiology
Migraine Disorders / diagnosis,  epidemiology,  genetics*,  physiopathology*,  therapy*
Physical Examination
Sodium-Potassium-Exchanging ATPase / genetics
Vestibular Diseases / diagnosis,  epidemiology,  genetics*,  physiopathology*,  therapy*
Vestibule, Labyrinth / physiopathology
Reg. No./Substance:
0/Calcium Channels; EC ATPase

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