Document Detail


Vestibular evoked myogenic potentials in patients with fibromyalgia syndrome.
MedLine Citation:
PMID:  20170583     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess vestibular evoked myogenic potentials in patients with fibromyalgia syndrome. METHODS: Twenty-four patients with fibromyalgia syndrome (two men and 22 women) and 21 female controls were included in the study. All patients underwent vestibular evoked myogenic potential testing. RESULTS: Statistical comparison of fibromyalgia patients with control subjects showed a significant difference with respect to n23 latencies and interpeak latencies (p < 0.05). There was no significant difference in p13 latencies, nor in p13 amplitudes, n23 amplitudes or interpeak amplitudes (p > 0.05). CONCLUSIONS: Although patients with fibromyalgia syndrome generally have subjective neurotological symptoms, clinical and laboratory assessments usually fail to detect any objective abnormality. However, it is possible to detect abnormalities on vestibular evoked myogenic potential testing in such patients, indicating dysfunction in the vestibulospinal pathway, possibly in the saccule. Elongation of the n23 latency and of the interpeak latency of waves p13-n23, during vestibular evoked myogenic potential testing, may be a useful, objective indicator demonstrating neurotological involvement in fibromyalgia syndrome patients. Future research investigating the mechanisms of this latency elongation may help increase understanding of the pathogenesis of fibromyalgia syndrome.
Authors:
Yildirim A Bayazit; F Celenk; A G Gunduz; B Gunduz; N Ondag; J Meray
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Publication Detail:
Type:  Journal Article     Date:  2010-02-22
Journal Detail:
Title:  The Journal of laryngology and otology     Volume:  124     ISSN:  1748-5460     ISO Abbreviation:  J Laryngol Otol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-24     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706896     Medline TA:  J Laryngol Otol     Country:  England    
Other Details:
Languages:  eng     Pagination:  610-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, Gazi University, Besevler, Cankaya, Ankara, Turkey. bayazity@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Electromyography
Evoked Potentials, Auditory / physiology*
Female
Fibromyalgia / physiopathology*
Humans
Male
Middle Aged
Muscle, Skeletal / physiology
Reaction Time
Vestibular Function Tests / methods
Vestibule, Labyrinth / physiology*
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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