Document Detail

Vesicourethral dysfunction and urodynamic findings in multiple sclerosis: a study of 149 cases.
MedLine Citation:
PMID:  9523775     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Vesicourethral dysfunction is common in people with multiple sclerosis and results in significant impairment. We studied the clinical and urodynamic findings in such patients to define risk factors for incontinence and upper urinary tract infections. DESIGN AND SETTING: A cohort study of 149 patients with multiple sclerosis and urinary symptoms seen in our urodynamic laboratory. INTERVENTION: A complete urodynamic study of each patient with urethrocystometry and continuous recording of the urethral sphincter electromyography and assessment of postvoid residual. RESULTS: Detrusor hyperreflexia and sphincter dyssynergia were the main dysfunctions. No significant relation between clinical features and urodynamic patterns was found. Women with low maximal urethral pressure were particularly prone to incontinence, which occurred in 69% of the patients. Pyelonephritis was associated with a postvoiding residual urine of > 30% of the functional detrusor capacity, and was found more often in the male population. CONCLUSION: Urodynamic assessment of bladder function is critical to direct therapy for urinary complaints in people with multiple sclerosis.
P Gallien; S Robineau; B Nicolas; M P Le Bot; R Brissot; M Verin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  79     ISSN:  0003-9993     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-04-08     Completed Date:  1998-04-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  255-7     Citation Subset:  AIM; IM    
Clinique de Rééducation Fonctionelle, Centre Hospitalier et Universitaire de Rennes, Hôpital Pontchaillou, France.
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MeSH Terms
Middle Aged
Multiple Sclerosis / complications*
Retrospective Studies
Risk Factors
Urinary Incontinence / etiology
Urinary Tract Infections / etiology
Vesico-Ureteral Reflux / complications*,  physiopathology*,  therapy
Comment In:
Arch Phys Med Rehabil. 1998 Nov;79(11):1481   [PMID:  9821915 ]

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