Document Detail

Vesicourethral dysfunction in multiple sclerosis.
MedLine Citation:
PMID:  470006     Owner:  NLM     Status:  MEDLINE    
Urodynamic evaluation was done 45 times on 41 consecutive patients with multiple sclerosis. Bladder symptoms correlated poorly with any single urodynamic finding and, accordingly, a comprehensive evaluation was necessary to define the underlying pathophysiology. Only 63 per cent of the patients with symptoms of urgency, frequency and urge incontinence actually were found to have uninhibited bladder contractions, while 73 per cent of the patients with obstructive symptoms had detrusor areflexia. Six patients (15 per cent) had a marked change in urodynamic findings upon repeat examination either because of a change in symptomatology or poor response to treatment. An additional 6 patients had vesicoureteral reflux. Bladder symptoms in multiple sclerosis patients should serve more to alert the clinician to the need for urodynamic testing than to mandate specific treatment.
J G Blaivas; G Bhimani; K B Labib
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of urology     Volume:  122     ISSN:  0022-5347     ISO Abbreviation:  J. Urol.     Publication Date:  1979 Sep 
Date Detail:
Created Date:  1979-10-26     Completed Date:  1979-10-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376374     Medline TA:  J Urol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  342-7     Citation Subset:  AIM; IM    
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MeSH Terms
Middle Aged
Multiple Sclerosis / complications,  physiopathology*
Prospective Studies
Urethra / physiopathology*
Urinary Bladder / physiopathology*
Urinary Bladder Diseases / etiology,  physiopathology
Urologic Diseases / etiology,  physiopathology*
Vesico-Ureteral Reflux / etiology,  physiopathology

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