Document Detail

Vesicoureteral reflux in children: a phantom study of microwave heating and radiometric thermometry of pediatric bladder.
MedLine Citation:
PMID:  21900069     Owner:  NLM     Status:  MEDLINE    
We have investigated the use of microwave heating and radiometry to safely heat urine inside a pediatric bladder. The medical application for this research is to create a safe and reliable method to detect vesicoureteral reflux, a pediatric disorder, where urine flow is reversed and flows from the bladder back up into the kidney. Using fat and muscle tissue models, we have performed both experimental and numerical simulations of a pediatric bladder model using planar dual concentric conductor microstrip antennas at 915 MHz for microwave heating. A planar elliptical antenna connected to a 500 MHz bandwidth microwave radiometer centered at 3.5 GHz was used for noninvasive temperature measurement inside tissue. Temperatures were measured in the phantom models at points during the experiment with implanted fiberoptic sensors, and 2-D distributions in cut planes at depth in the phantom with an infrared camera at the end of the experiment. Cycling between 20 s with 20 Watts power for heating, and 10 s without power to allow for undisturbed microwave radiometry measurements, the experimental results show that the target tissue temperature inside the phantom increases fast and that the radiometer provides useful measurements of spatially averaged temperature of the illuminated volume. The presented numerical and experimental results show excellent concordance, which confirms that the proposed system for microwave heating and radiometry is applicable for safe and reliable heating of pediatric bladder.
Yngve Birkelund; Øystein Klemetsen; Svein K Jacobsen; Kavitha Arunachalam; Paolo Maccarini; Paul R Stauffer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-09-06
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  58     ISSN:  1558-2531     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-10-19     Completed Date:  2012-02-23     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3269-78     Citation Subset:  IM    
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MeSH Terms
Adipose Tissue / physiology
Child, Preschool
Computer Simulation
Hyperthermia, Induced / instrumentation,  methods*
Models, Biological*
Muscles / physiology
Phantoms, Imaging*
Radiometry / instrumentation,  methods*
Urinary Bladder / physiology*
Vesico-Ureteral Reflux / diagnosis*
Grant Support
R01 CA070761/CA/NCI NIH HHS; R01 CA070761-09/CA/NCI NIH HHS; R21 DK092912/DK/NIDDK NIH HHS; R21 DK092912-01/DK/NIDDK NIH HHS

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