| Very late recurrences of leukemia: why does leukemia awake after many years of dormancy? | |
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MedLine Citation:
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PMID: 20970853 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a heterogeneous group of very late recurrences of leukemia occurring more than 10 years after initial treatment including 2 cases of childhood acute lymphoblastic leukemia (ALL) which recurred after more than 20 years of remission, 2 cases of donor cell leukemia which developed more than 10 years after allograft for acute myeloid leukemia (AML) and high risk myelodysplastic syndrome (MDS) and 2 cases of chronic myeloid leukemia (CML) relapsing 13 and 17 years after allograft. Case descriptions are followed by a discussion regarding possible mechanisms leading to leukemia recurrence and a review of the literature. |
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Authors:
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Maxim Norkin; Joseph P Uberti; Charles A Schiffer |
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Publication Detail:
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Type: Case Reports; Letter; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Leukemia research Volume: 35 ISSN: 1873-5835 ISO Abbreviation: Leuk. Res. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-25 Completed Date: 2011-03-09 Revised Date: 2011-10-19 |
Medline Journal Info:
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Nlm Unique ID: 7706787 Medline TA: Leuk Res Country: England |
Other Details:
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Languages: eng Pagination: 139-44 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Division of Hematology and Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI 48201, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Child Female Humans Leukemia* / genetics, pathology, therapy Male Middle Aged Neoplasms, Second Primary / genetics, pathology, therapy Recurrence Stem Cell Transplantation |
| Comments/Corrections | |
Comment In:
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Leuk Res. 2011 Jun;35(6):e73-4
[PMID:
21163527
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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