Document Detail


Very late isolated CNS relapse of acute myeloid leukemia.
MedLine Citation:
PMID:  23412589     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Isolated central nervous system (CNS) relapse in acute myeloid leukemia (AML) rarely occurs later than 2 years after remission. We present a child diagnosed with AML (FAB M5) without CNS involvement at diagnosis who was treated with chemotherapy and consolidated with autologous hematopoietic stem cell transplantation. He was in complete remission for >6 years until he had an isolated CNS relapse. He was treated with only intrathecal chemotherapy and achieved a second complete remission, but relapsed in the bone marrow 5 months after the CNS relapse. Treatment of late isolated CNS relapse of AML is discussed.
Authors:
Blanca Molina; Alvaro Lassaletta; Marta Gonzalez-Vicent; Maitane Andión; Miguel A Diaz; Luis Madero
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  35     ISSN:  1536-3678     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e57-9     Citation Subset:  IM    
Affiliation:
Pediatric Hematology Oncology Department, Hospital Niño Jesús, Madrid, Spain.
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