Document Detail

Very early acute myocardial infarct treated with streptokinase and balloon angioplasty.
MedLine Citation:
PMID:  1531326     Owner:  NLM     Status:  MEDLINE    
A 57-year-old man developed anginalike chest pain for the first time but there was no objective evidence of an infarct (i.e., EKG and serum enzymes were normal). After 12 days the pain increased, but EKG and serum enzymes remained normal ("preinfarct," crescendo, unstable, or accelerated angina). At this time a cardiac catheterization showed 90% occlusion of the left anterior descending (LAD) coronary artery. On the 17th day after the onset of pain, severe pain recurred together with an abnormal EKG and the patient was taken immediately to the laboratory where a total occlusion of the LAD was now found and he was treated with intracoronary streptokinase. The artery remained open for only a short time, and balloon angioplasty was performed. However, the patient died 12 hours after onset of the last episode of severe pain. A very early acute myocardial infarct was diagnosed at autopsy together with severe coronary atherosclerosis especially of the LAD which had disruption of atherosclerotic plaques and microscopic evidence of embolization.
D B Hackel; G Wagner
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical cardiology     Volume:  15     ISSN:  0160-9289     ISO Abbreviation:  Clin Cardiol     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-03-17     Completed Date:  1992-03-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7903272     Medline TA:  Clin Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  109-13     Citation Subset:  IM    
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710.
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MeSH Terms
Angioplasty, Balloon*
Coronary Artery Disease / drug therapy,  pathology,  therapy
Middle Aged
Myocardial Infarction / drug therapy,  pathology,  therapy*
Myocardium / pathology
Streptokinase / therapeutic use*
Time Factors
Reg. No./Substance:
EC 3.4.-/Streptokinase

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