Document Detail


Vertical-cavity semiconductor devices for fluorescence spectroscopy in biochips and microfluidic platforms.
MedLine Citation:
PMID:  16229645     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This paper describes the properties of vertical-cavity semiconductor devices designed to emit light when driven in forward bias mode and detect optical radiation at wavelengths longer than that of emission when driven in reverse bias mode. The study of this type of devices is motivated by the miniaturization and integration into a single unit of the three functions that a microfluorimeter has to perform, optical pumping, optical detection, and optical filtering of weak light sources. The devices produced can generate fluorescence with a low output power since their emission wavelength can be tuned with that of maximum absorption of the fluorescent dye. We demonstrate also that they can detect low power fluorescence generated in a small volume of concentrated solution of a commercial dye. These devices can find useful application in microanalytical systems such as microfluidic devices or optical biochips.
Authors:
P A Porta; H D Summers
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of biomedical optics     Volume:  10     ISSN:  1083-3668     ISO Abbreviation:  J Biomed Opt     Publication Date:    2005 May-Jun
Date Detail:
Created Date:  2005-10-18     Completed Date:  2005-11-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9605853     Medline TA:  J Biomed Opt     Country:  United States    
Other Details:
Languages:  eng     Pagination:  034001     Citation Subset:  IM    
Copyright Information:
2005 Society of Photo-Optical Instrumentation Engineers.
Affiliation:
Cardiff University, School of Physics and Astronomy, 5, The Parade, Cardiff, CF24 3YB Wales, United Kingdom. portapa@cf.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Biosensing Techniques / instrumentation*,  methods
Equipment Design
Equipment Failure Analysis
Lighting / instrumentation*,  methods
Microfluidic Analytical Techniques / instrumentation*,  methods
Semiconductors*
Spectrometry, Fluorescence / instrumentation*,  methods
Systems Integration
Transducers*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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