Document Detail

Vertebroplasty for metastasis.
MedLine Citation:
PMID:  14514969     Owner:  NLM     Status:  MEDLINE    
Vertebral metastases are frequently asymptomatic; however, the occurrence of a pathological (micro-)fracture may be associated with unremitting pain, instability, and even kyphoscoliotic deformity and require prompt and effective treatment. In symptomatic patients, the beneficial effect of conservative therapies requires too much time. Vertebroplasty (VP) may be an additional or even alternative local treatment modality for such patients. Currently, up to 80% of VP patients report important relief of metastasis-related pain. Ongoing deformity of the vertebral body is avoided. Morbidity rates are very low and the complication rates are markedly below 10%. Fatalities, if any, are almost always the result of cancer comorbidity rather than related to the VP procedure itself. The patient's mobility is often improved, thus avoiding much of the comorbidity of prolonged conservative treatment and bed rest. VP can successfully be combined with chemotherapy, radiotherapy, neurodecompression, and instrumentation. Even though VP is no panacea, it may be helpful to selected patients and instantly improve quality of life. Currently, VP has a solid basis for the palliative treatment of thoracic, lumbar, and sacral metastasis.
Markus Wenger
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Medical oncology (Northwood, London, England)     Volume:  20     ISSN:  1357-0560     ISO Abbreviation:  Med. Oncol.     Publication Date:  2003  
Date Detail:
Created Date:  2003-09-29     Completed Date:  2004-02-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9435512     Medline TA:  Med Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  203-9     Citation Subset:  IM    
Neurosurgery, The Hirslanden Group, Klinik Beau-Site, Schänzlihalde 11-13, CH-3000 Bern 25, Switzerland.
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MeSH Terms
Lumbar Vertebrae / pathology,  surgery
Orthopedic Procedures
Sacrum / pathology,  surgery
Spinal Neoplasms / secondary*,  surgery*
Thoracic Vertebrae / pathology,  surgery

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