Document Detail


Vertebrate intestinal endoderm development.
MedLine Citation:
PMID:  21246663     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The endoderm gives rise to the lining of the esophagus, stomach and intestines, as well as associated organs. To generate a functional intestine, a series of highly orchestrated developmental processes must occur. In this review, we attempt to cover major events during intestinal development from gastrulation to birth, including endoderm formation, gut tube growth and patterning, intestinal morphogenesis, epithelial reorganization, villus emergence, as well as proliferation and cytodifferentiation. Our discussion includes morphological and anatomical changes during intestinal development as well as molecular mechanisms regulating these processes.
Authors:
Jason R Spence; Ryan Lauf; Noah F Shroyer
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review     Date:  2011-01-18
Journal Detail:
Title:  Developmental dynamics : an official publication of the American Association of Anatomists     Volume:  240     ISSN:  1097-0177     ISO Abbreviation:  Dev. Dyn.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-21     Completed Date:  2011-08-01     Revised Date:  2013-05-27    
Medline Journal Info:
Nlm Unique ID:  9201927     Medline TA:  Dev Dyn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  501-20     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Wiley-Liss, Inc.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Differentiation / physiology
Endoderm / cytology*,  embryology*,  metabolism
Humans
Intestines / cytology*,  embryology*,  metabolism
Mesoderm / cytology,  embryology,  metabolism
Vertebrates / embryology*,  growth & development*
Grant Support
ID/Acronym/Agency:
F32 DK083202-02/DK/NIDDK NIH HHS; F32 DK83202-01/DK/NIDDK NIH HHS; R01 CA142826/CA/NCI NIH HHS; R01 CA142826/CA/NCI NIH HHS; R01 CA142826-01/CA/NCI NIH HHS; R03 DK084167/DK/NIDDK NIH HHS; R03 DK084167-02/DK/NIDDK NIH HHS; T32 HD007463-15/HD/NICHD NIH HHS; T32 HD07463/HD/NICHD NIH HHS
Comments/Corrections

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