Document Detail

Vertebral bone mineral density measured laterally by dual-energy X-ray absorptiometry.
MedLine Citation:
PMID:  2133636     Owner:  NLM     Status:  MEDLINE    
The bone mineral density (BMD) of lumbar vertebrae in the anteroposterior (AP) view may be overestimated in osteoarthritis or with aortic calcification, which are common in elderly. Furthermore, the risk of spinal crush fracture should be more closely related inversely to the BMD of the vertebral body than to that of the posterior arch. Therefore, we measured BMD of lumbar vertebrae in lateral (LAT) view (L2-L3), using a standard dual-energy X-ray absorptiometer (DEXA), thus eliminating most of the posterior spinal elements. The precision of BMD LAT measurement was determined both in vitro and in healthy volunteers. Then, we compared the capability of BMD LAT and BMD AP scans for monitoring bone loss related to age and for discriminating the BMD of postmenopausal women with nontraumatic vertebral fractures from that of young subjects. In vitro, when a spine phantom was placed in lateral position in the middle of 26 cm of water in order to simulate both soft-tissue thickness and X-ray source remoteness, the coefficient of variation (CV) of six repeated determinations of BMD was 1.0%. In vivo, the CV of paired BMD LAT measurements obtained in 20 healthy volunteers after repositioning was 2.8%. The age-related difference between a peak bone mass group estimated in a group of 27 healthy women aged 20 to 35 years and a group of 50 women aged 60 to 75 years, in whom neither vertebral fracture nor osteoporosis risk factors could be detected, were 21.7% and 37.6% in AP and LAT view, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
D O Slosman; R Rizzoli; A Donath; J P Bonjour
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA     Volume:  1     ISSN:  0937-941X     ISO Abbreviation:  Osteoporos Int     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1992-03-31     Completed Date:  1992-03-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9100105     Medline TA:  Osteoporos Int     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  23-9     Citation Subset:  IM; S    
Department of Radiology, University Hospital, Geneva, Switzerland.
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MeSH Terms
Absorptiometry, Photon / methods
Bone Density*
Lumbar Vertebrae / physiology,  radiography*
Middle Aged

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