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Vertebral Langerhans cell histiocytosis in an adult patient: case report and review of the literature.
MedLine Citation:
PMID:  21667741     Owner:  NLM     Status:  In-Process    
Vertebral Langerhans cell histiocytosis, formerly called Histiocytosis X, is rarely seen in adults: a systematic non-quantitative review of the literature yielded only 27 cases. Vertebra plana is often associated in children, but this is not a feature in the adult population. The authors report the case of a 29-year-old woman with a two-month history of lumbar pain. Osteolysis of the right pedicle of L2 was noted on CT and MRI. Transpedicular curettage and fusion L1L3 were performed. Histopathological examination revealed Langerhans cell histiocytosis. Although rare, Langerhans cell histiocytosis should be included in the differential diagnosis of the solitary lytic vertebral lesion in the adult. Good results have been reported, in the absence of systemic manifestations, with the most conservative approach possible.
George Sapkas; Michael Papadakis
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta orthopaedica Belgica     Volume:  77     ISSN:  0001-6462     ISO Abbreviation:  Acta Orthop Belg     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-06-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985165R     Medline TA:  Acta Orthop Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  260-4     Citation Subset:  IM    
University of Athens and the Metropolitan Hospital, Athens, Greece.
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