Document Detail


Vertebral artery hypoplasia: prevalence and reliability of identifying and grading its severity on magnetic resonance imaging scans.
MedLine Citation:
PMID:  20350674     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study is to examine the inter- and intraexaminer reliability of determining the prevalence of vertebral artery hypoplasia on magnetic resonance imaging (MRI) as well as the reliability of assigning a severity grading of mild, moderate, or marked hypoplasia. METHODS: Two chiropractic radiologists independently evaluated the MR images of 131 adult patients retrospectively for visual vertebral artery hypoplasia. Severity of hypoplastic was graded. The side of hypoplasia and sex of the patient were recorded. The process was repeated after 1 month. Descriptive statistics were calculated for prevalence, severity, and sex distribution of hypoplasia. The kappa statistic was calculated for the reliability of detecting and grading the hypoplasia. RESULTS: Interexaminer reliability was substantial for both readings (kappa = 0.68, 83% agreement for the first reading; kappa = 0.75, 86% agreement for the second reading). Interexaminer reliability for grading the severity of asymmetry was substantial (kappa = 0.73, 83% agreement for the first read; kappa = 0.69, 81% agreement for the second reading). Intraexaminer reliability readings provided a kappa of 0.71 (substantial) and 83% agreement for examiner 1. Examiner 2 had a kappa of 0.85 (almost perfect) with 92% agreement. Overall, 57 (43.5%) of the 131 patients demonstrated hypoplasia. Hypoplasia was more common in women (49%) than men (35.8%). Seven arteries demonstrated severe hypoplasia. Six of these 7 patients were women. CONCLUSIONS: Vertebral artery hypoplasia is common and can be reliably diagnosed and categorized on cervical MRI scans. Vertebral artery hypoplasia was more common in women than men in this group of patients.
Authors:
Cynthia Peterson; Lee Phillips; Ashleah Linden; William Hsu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of manipulative and physiological therapeutics     Volume:  33     ISSN:  1532-6586     ISO Abbreviation:  J Manipulative Physiol Ther     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807107     Medline TA:  J Manipulative Physiol Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  207-11     Citation Subset:  IM    
Copyright Information:
Copyright 2010 National University of Health Sciences. Published by Mosby, Inc. All rights reserved.
Affiliation:
Director, Swiss Academy for Chiropractic, Bern, Switzerland and former Professor, Canadian Memorial Chiropractic College, Toronto, Ontario, Canada. cindy.peterson@chirosuisse.ch
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MeSH Terms
Descriptor/Qualifier:
Aged
Atrophy / epidemiology,  pathology
Brain Ischemia / pathology*
Female
Humans
Magnetic Resonance Imaging*
Male
Middle Aged
Prevalence
Reproducibility of Results
Retrospective Studies
Severity of Illness Index
Vertebral Artery / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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