Document Detail

Verrucous carcinoma due to arsenic ingestion in a psoriasis patient.
MedLine Citation:
PMID:  23149204     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVE: Verrucous carcinoma is a rare clinicopathologic entity caused by multifactorial influences. We report here a 64-year-old male patient presenting with a large exophytic mass in the right leg.
RESULTS AND CONCLUSION: The patient had a 19-year duration of psoriasis and received various treatments. In his last year of life, he had been taking an illegally produced folk drug with the hope of controlling his psoriasis. However, 6 months after the drug ingestion, many papules appeared on his right leg, which eventually developed into a large tumor in the next few months. The patient died of acute pulmonary embolism only a week after hospitalization, when his tumor was pathologically confirmed as verrucous carcinoma. Later, the folk drug was analyzed and found to contain arsenic. The causative relevance of the tumor with his daily arsenic intake is discussed.
Jian-Wei Zhu; Min Zheng
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cutaneous medicine and surgery     Volume:  16     ISSN:  1203-4754     ISO Abbreviation:  J Cutan Med Surg     Publication Date:    2012 Nov-Dec
Date Detail:
Created Date:  2012-11-15     Completed Date:  2013-04-16     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  9614685     Medline TA:  J Cutan Med Surg     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  445-7     Citation Subset:  IM    
Department of Dermatology, Second Affiliated Hospital, Zhejiang University, School of Medicine, Hangzhou 310009, China.
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MeSH Terms
Arsenic / adverse effects*,  therapeutic use
Carcinoma, Verrucous / chemically induced*,  pathology
Fatal Outcome
Medicine, Traditional / adverse effects*
Middle Aged
Psoriasis / drug therapy
Skin Neoplasms / chemically induced*,  pathology
Reg. No./Substance:

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