Document Detail


Verapamil sensitive incessant ventricular tachycardia in the newborn.
MedLine Citation:
PMID:  8946465     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Incessant VTs in infancy are often poorly tolerated. Response to conventional antiarrhythmic therapy is disappointing. The present case involves a 3-week-old infant with an incessant VT of a left bundle branch block, and normal axis morphology. This tachycardia was inducible with both atrial and ventricular pacing, but not by premature stimulation. Tachycardia persisted despite treatment with adenosine, esmolol, procainamide, and flecainide. Intravenous verapamil suppressed tachycardia and prevented inducibility, and no further recurrences were seen on oral verapamil. This case suggests that some incessant VTs in infancy may be due to calcium channel related afterdepolarizations or triggered activation.
Authors:
A Dhala; D A Lewis; J Garland; A N Pelech
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  19     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1996 Nov 
Date Detail:
Created Date:  1997-04-08     Completed Date:  1997-04-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1652-4     Citation Subset:  IM    
Affiliation:
Electrophysiology Laboratory, Children's Hospital of Wisconsin, Milwaukee, USA.
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MeSH Terms
Descriptor/Qualifier:
Anti-Arrhythmia Agents / therapeutic use*
Bundle-Branch Block / complications
Calcium Channel Blockers / therapeutic use*
Electrocardiography
Female
Humans
Infant, Newborn
Infant, Premature, Diseases / diagnosis,  drug therapy*,  etiology
Recurrence
Tachycardia, Ventricular / diagnosis,  drug therapy*,  etiology
Verapamil / therapeutic use*
Chemical
Reg. No./Substance:
0/Anti-Arrhythmia Agents; 0/Calcium Channel Blockers; 52-53-9/Verapamil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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