| Verapamil: a new antimanic drug with potential interactions with lithium. | |
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MedLine Citation:
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PMID: 3114243 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Verapamil is a calcium channel blocking agent with possible antimanic properties. In two elderly manic patients taking the medication in combination with lithium carbonate, profound bradycardia developed and was followed by a fatal myocardial infarction in one case. Clinical implications and possible mechanisms of cardiovascular interactions between verapamil and lithium are discussed. Caution is advised in the use of lithium and verapamil together. |
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Authors:
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S L Dubovsky; R D Franks; S Allen |
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7056703 - Cardiac effects of lithium therapy in man: a review. 1148053 - Electron microscopical study of myocardial biopsy material in congenital heart block. 2727983 - Postinfarction ventricular septal defect--surgical strategies and results. |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of clinical psychiatry Volume: 48 ISSN: 0160-6689 ISO Abbreviation: J Clin Psychiatry Publication Date: 1987 Sep |
Date Detail:
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Created Date: 1987-10-08 Completed Date: 1987-10-08 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7801243 Medline TA: J Clin Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 371-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Arrhythmias, Cardiac / chemically induced Bipolar Disorder / drug therapy* Bradycardia / chemically induced Drug Interactions Drug Therapy, Combination Female Humans Lithium / adverse effects*, therapeutic use Lithium Carbonate Male Verapamil / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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52-53-9/Verapamil; 554-13-2/Lithium Carbonate; 7439-93-2/Lithium |
| Comments/Corrections | |
Comment In:
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J Clin Psychiatry. 1989 Dec;50(12):473
[PMID:
2600068
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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