Document Detail

Verapamil infusions in the treatment of atrial tachyarrhythmias.
MedLine Citation:
PMID:  3757529     Owner:  NLM     Status:  MEDLINE    
Ten patients with symptomatic atrial tachyarrhythmias were treated with an iv verapamil bolus (mean 8.5 mg) followed by a continuous verapamil infusion (mean dose 9.4 mg/h). The infusions were titrated to ventricular rate and continued for an average of 20 h, until oral therapy could be instituted. All patients had a significant, sustained reduction in ventricular rate during the infusion, without a significant reduction in mean arterial pressure. Although one patient complained of dizziness after 8 h of infusion therapy, the regimen was generally well tolerated and no patient had clinical worsening of heart failure. These preliminary data suggest that continuous verapamil infusions can safely and effectively control ventricular rate in patients with rapid atrial tachyarrhythmias, until oral medications can be started.
R A Barbarash; J L Bauman; A A Lukazewski; J P Srebro; S Rich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  14     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-10-30     Completed Date:  1986-10-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  886-8     Citation Subset:  AIM; IM    
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MeSH Terms
Aged, 80 and over
Blood Pressure / drug effects
Heart Rate / drug effects
Infusions, Intravenous
Injections, Intravenous
Tachycardia, Supraventricular / drug therapy*
Verapamil / administration & dosage*,  adverse effects
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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