Document Detail

Ventricular tachycardia/fibrillation: therapeutic alternatives.
MedLine Citation:
PMID:  1706855     Owner:  NLM     Status:  MEDLINE    
It is now clear that no single therapy is appropriate for a consecutive series of patients with ventricular tachycardia or ventricular fibrillation (VT/VF). Drug responders by electrophysiological studies, patients who are not inducible following surgery, and patients treated with an implantable cardioverter defibrillator (ICD) all can have similarly low sudden death rates and virtually identical long-term mortality. However, many patients fail to respond to drugs, and surgical risks are excessive in others, and always higher than for an ICD implant. Nevertheless, overall survival in each of these groups (and probably for patients treated with antitachycardia pacers and ablation) is about 60% at 60 months. Major challenges now are: (1) choosing therapy to maximize risk-benefit ratio; and (2) treatment of the pump failure and progressive disease that now accounts for most cardiac mortality.
J D Fisher; S G Kim; J A Roth; K J Ferrick; R F Brodman; J N Gross; S Furman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  14     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-04-29     Completed Date:  1991-04-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  370-5     Citation Subset:  IM    
Department of Medicine, Montefiore Medical Center, Bronx, New York 10467.
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MeSH Terms
Anti-Arrhythmia Agents / therapeutic use
Combined Modality Therapy
Electric Countershock / instrumentation
Pacemaker, Artificial
Prostheses and Implants
Tachycardia / therapy*
Ventricular Fibrillation / therapy*
Reg. No./Substance:
0/Anti-Arrhythmia Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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