Document Detail

Ventricular septal rupture: a review of clinical and physiologic features and an analysis of survival.
MedLine Citation:
PMID:  7020978     Owner:  NLM     Status:  MEDLINE    
Forty-one patients with postinfarction ventricular septal rupture were cared for in our hospital during 1971-1975. Cardiogenic shock developed after septal rupture in 55% of these patients. Shock was unrelated to site of infarction, extent of coronary artery disease, left ventricular ejection fraction, or pulmonary-to-systemic flow ratio, but mean pulmonary artery pressure was lower in shock than in nonshock patients. These observations suggest that shock was produced mainly by right ventricular impairment. Perioperative survival was much higher in patients who did not have shock preoperatively (14 of 17 [82+]) than in those who did (three of 11 [27%]). Magnitude of shunt, left ventricular ejection fraction, extent of coronary artery disease, and performance of aortocoronary bypass grafting were not distinctly correlated with perioperative survival. After a minimum 4-year follow-up, 76% of the perioperative survivors are alive, and none suffer more than New York Heart Association functional class II disability. All 13 unoperated patients (11 in shock) died within 3 months.
M J Radford; R A Johnson; W M Daggett; J T Fallon; M J Buckley; H K Gold; R C Leinbach
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Circulation     Volume:  64     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1981 Sep 
Date Detail:
Created Date:  1981-10-25     Completed Date:  1981-10-25     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  545-53     Citation Subset:  AIM; IM    
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MeSH Terms
Blood Pressure
Coronary Artery Bypass
Follow-Up Studies
Heart Rupture / etiology*,  radiography,  surgery
Heart Septum*
Heart Ventricles / physiopathology
Middle Aged
Myocardial Infarction / complications*
Pulmonary Artery
Shock / etiology
Stroke Volume
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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