| Ventricular septal flattening at end systole falsely predicts right ventricular hypertension in patients with ostium primum atrial septal defects. | |
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MedLine Citation:
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PMID: 11875388 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To assess the reliability of ventricular septal position in predicting elevated right ventricular pressure (RVP) in patients with ostium primum atrial septal defects (ASD 1). METHODS: Echocardiograms of 4 groups were retrospectively analyzed: Patients with ASD 1 and low RVP, patients with ASD 1 and high RVP, and 2 age-matched control groups: one with isolated ostium secundum atrial septal defects (ASD 2), and 1 with normal cardiac findings. End-systolic left ventricular sectional diameters along the midmitral diameter (D1) and a diameter orthogonal to it (D2) were measured off-line by a blinded observer. The ratio D2/D1, the eccentricity index (EI), was calculated; a higher index represents greater septal flattening. RESULTS: The mean EI in the ASD 1 with low RVP group was significantly higher than both the group with ASD 2 and the healthy control group. The mean EI of the ASD 1 group with high RVP was significantly higher than the mean EI of the ASD 1 group with low RVP, although there was a poor correlation between EI and RVP in this group, r = 0.54. CONCLUSION: The ventricular septum is flatter in the ASD 1 patients with low RVP than in an age-matched control group with ASD 2 and compared with an age-matched control group of healthy subjects, giving a false impression of elevated RVP in the ASD 1 group. Although the mean EI is significantly higher in the ASD 1 group with high RVP than in the group with low RVP, there is a poor correlation between EI and RVP, which limits the reliability of this index. |
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Authors:
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James C Nielsen; Steven A Kamenir; Hyun-Sook H Ko; Wyman W Lai; Ira A Parness |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 15 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2002 Mar |
Date Detail:
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Created Date: 2002-03-04 Completed Date: 2002-04-23 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 247-52 Citation Subset: IM |
Affiliation:
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Division of Pediatric Cardiology, Mount Sinai Medical Center, New York, NY 10029, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Case-Control Studies Child Child, Preschool Cohort Studies Echocardiography Heart Septal Defects, Atrial / physiopathology* Heart Ventricles / physiopathology* Hemodynamics Humans Hypertension / diagnosis*, physiopathology Observer Variation Retrospective Studies Systole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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