Document Detail

Ventricular septal defect with overriding aorta in trisomy-18.
MedLine Citation:
PMID:  3409935     Owner:  NLM     Status:  MEDLINE    
In a child with trisomy-18 prenatal echocardiography demonstrated the presence of a ventricular septal defect with overriding aorta. In a previous anatomical study of 18 hearts with this malformation we found a 50% concurrence rate with trisomy-18. In case of prenatal echocardiographic detection of a ventricular septal defect with overriding aorta, we advise thorough ultrasound examination for additional malformations as seen in trisomy-18; subsequently this procedure should be completed by cytogenetic analysis of amniotic cells.
R J Moene; M Sobotka-Plojhar; A Oppenheimer-Dekker; D Lindhout
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  147     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-09-29     Completed Date:  1988-09-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  556-7     Citation Subset:  IM    
Department of Paediatric Cardiology, Free University Hospital, Amsterdam, The Netherlands.
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MeSH Terms
Aorta / abnormalities*
Chromosomes, Human, Pair 18*
Heart Septal Defects, Ventricular / complications*,  diagnosis,  pathology
Infant, Newborn
Prenatal Diagnosis

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