Document Detail

Ventricular remodeling in Loeffler endocarditis: implications for therapeutic decision making.
MedLine Citation:
PMID:  16188499     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Little is known about the morphological and functional evolution of ventricular abnormalities in Loeffler endocarditis.
METHODS AND RESULTS: We describe 5 patients, including 3 with long-term echocardiographic follow-up, in whom apical obliteration due to fibro-thrombotic thickening of the endocardium showed favorable patterns of evolution. In one patient there was almost complete resolution of the obliterative process with consequently increased effective ventricular volume. In two patients formation of a flow-passage in the fibrocalcific apical 'floor' between the main medioventricular cavity and the apical chamber, leading to a 'double-chambered' left ventricle was observed.
CONCLUSIONS: Medical therapy and appropriate anticoagulation, can induce favorable long-term ventricular remodeling in Loeffler endocarditis.
Carla Lofiego; Marinella Ferlito; Guido Rocchi; Elena Biagini; Enrica Perugini; Angelo Branzi; Claudio Rapezzi
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2005-09-26
Journal Detail:
Title:  European journal of heart failure     Volume:  7     ISSN:  1388-9842     ISO Abbreviation:  Eur. J. Heart Fail.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-17     Completed Date:  2006-01-23     Revised Date:  2011-06-08    
Medline Journal Info:
Nlm Unique ID:  100887595     Medline TA:  Eur J Heart Fail     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1023-6     Citation Subset:  IM    
Institute of Cardiology, University of Bologna, Policlinico S. Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy.
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MeSH Terms
Decision Making
Disease Progression
Echocardiography, Doppler, Color / methods*
Follow-Up Studies
Hypereosinophilic Syndrome / physiopathology,  therapy*,  ultrasonography*
Hypertrophy, Left Ventricular / physiopathology,  ultrasonography*
Middle Aged
Risk Assessment
Sampling Studies
Severity of Illness Index
Ventricular Function, Left / physiology
Ventricular Remodeling / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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