Document Detail


Ventricular relaxation and mitral opening time in various ventricular conditions of old age.
MedLine Citation:
PMID:  1218736     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This phonocardiographic-echocardiographic study was based on measurement of the interval between the aortic component of the second sound (IIA) and the peak of the E wave of the mitral echogram. The study was performed in 20 cases of left bundle branch block (LBBB), 10 cases of right bundle branch block (RBBB), 10 cases of old myocardial infarct (MI), and 10 cases of systemic hypertension (HY). All patients were above 60 years of age, and their data were compared with those of old persons without evidence of heart disease serving as controls. The IIA-E interval was found markedly prolonged in LBBB, less prolonged in MI and RBBB, and was shortened in HY. A dynamic analysis revealed that this interval results from the isovolumic relaxation period (IRP) of the left ventricle plus the "opening time" of the mitral valve. The changes observed were explained as resulting from a modification of the IRP that should be correlated with a similar modification of the isovolumic contraction time. Myocardial fibrosis would cause prolongation of IRP through structural lesions while hypertension would cause abbreviation of IRP through hormonal effects modifying both contraction and relaxation.
Authors:
A A Luisada; P K Bhat; K Watanabe; D B Rao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Gerontologia clinica     Volume:  17     ISSN:  0016-8998     ISO Abbreviation:  Gerontol Clin (Basel)     Publication Date:  1975  
Date Detail:
Created Date:  1976-05-25     Completed Date:  1976-05-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7601653     Medline TA:  Gerontol Clin (Basel)     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  181-90     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Analysis of Variance
Bundle-Branch Block / physiopathology
Echocardiography
Female
Heart Diseases / physiopathology*
Humans
Hypertension / physiopathology
Male
Mitral Valve / physiopathology*
Myocardial Infarction / physiopathology
Phonocardiography
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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