Document Detail

Ventricular intramyocardial electrograms and their expected potential for cardiac risk surveillance, telemonitoring, and therapy management.
MedLine Citation:
PMID:  19273022     Owner:  NLM     Status:  MEDLINE    
Ventricular intramyocardial electrograms are recorded with electrodes directly from the heart either in intraventricular or epimyocardial position and may be acquired either from the spontaneously beating or from the paced heart. The morphology of these signals differs significantly from that of body surface ECG recordings. Although the morphology shows general characteristics, it additionally depends on different individual impacts. This problem of individual evaluation is briefly discussed. As an appropriate methodology for its solution, personalized referencing based on similarity averaging has been employed. A more general approach may be model-based signal interpretation, which is still under investigation. The preliminary results reveal a promising potential of intramyocardial electrograms for cardiac risk surveillance, e.g., for arrhythmia detection, recognition of rejection events in transplanted hearts, and assessment of hemodynamic performance. Employing implants with telemetric capabilities may render possible permanent and even continuous cardiac telemonitoring. Furthermore, the signals can be utilized for supporting therapy management, e.g., in patients with different kinds of cardiomyopathies. This paper shall demonstrate some preliminary results and discuss the expected potential.
Helmut Hutten
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-02-02
Journal Detail:
Title:  IEEE transactions on information technology in biomedicine : a publication of the IEEE Engineering in Medicine and Biology Society     Volume:  13     ISSN:  1558-0032     ISO Abbreviation:  IEEE Trans Inf Technol Biomed     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-07-09     Completed Date:  2009-10-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9712259     Medline TA:  IEEE Trans Inf Technol Biomed     Country:  United States    
Other Details:
Languages:  eng     Pagination:  426-32     Citation Subset:  IM    
Institute of Medical Erngineering, Graz University of Technology, A-8010 Graz, Austria.
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MeSH Terms
Electrophysiologic Techniques, Cardiac / methods*
Graft Rejection / physiopathology
Heart / physiopathology*
Heart Transplantation
Heart Ventricles / physiopathology
Monitoring, Physiologic / methods
Patient Care Management / methods
Signal Processing, Computer-Assisted*
Telemedicine / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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