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Ventricular hypertrophy and cardiovascular mortality in hemodialysis patients with low educational level.
MedLine Citation:
PMID:  22218412     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Left ventricular hypertrophy is a strong predictor of mortality in chronic kidney patients. A previous study of our group has shown that chronic kidney patients with low educational level has more severe ventricular hypertrophy. OBJECTIVE: To extend a previous study and to assess whether left ventricular hypertrophy can explain the association between schooling and cardiovascular mortality in hemodialysis patients. METHODS: This study assessed 113 patients from January 2005 to March 2008 and followed them up until October 2010. Survival curves were built to compare all-cause and cardiovascular mortality of patients with up to three years of schooling (median schooling) and those with schooling of four years and over. Cox multiple models were built and adjusted to confounding variables. RESULTS: Association between educational level and ventricular hypertrophy was observed. Statistical difference in all-cause and cardiovascular mortality between the different educational levels was observed at 5.5 years of follow-up. In the Cox model, ventricular hypertrophy and C-reactive protein associated with all-cause and cardiovascular mortality. The etiology of kidney failure associated with all-cause mortality, and creatinine associated with cardiovascular mortality. The association between educational level and mortality lost statistical significance in the adjusted model. CONCLUSION: The results of this study confirm those of a previous study. In addition, they show that the higher cardiovascular mortality observed in patients with low educational level can be explained by risk factors of biochemical and cardiac morphological origin.
Authors:
Rosana Dos Santos E Silva Martin; Luis Cuadrado Martin; Roberto Jorge da Silva Franco; Pasqual Barretti; Jacqueline Costa Teixeira Caramori; João Henrique Castro; Aline de Araújo Antunes; Silméia Garcia Zanati-Basan; Beatriz Bojikian Matsubara; Antônio Sérgio Martins
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-06
Journal Detail:
Title:  Arquivos brasileiros de cardiologia     Volume:  -     ISSN:  1678-4170     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421031     Medline TA:  Arq Bras Cardiol     Country:  -    
Other Details:
Languages:  ENG; POR     Pagination:  -     Citation Subset:  -    
Affiliation:
Departamento de Enfermagem, Faculdade de Medicina de Botucatu, UNESP, SP, Brasil.
Vernacular Title:
Hipertrofia ventricular e mortalidade cardiovascular em pacientes de hemodiálise de baixo nível educacional.
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