Document Detail

Ventricular gradient variability. New ECG method for detection of ischemic heart disease.
MedLine Citation:
PMID:  7595119     Owner:  NLM     Status:  MEDLINE    
The usefulness of ventricular gradient variability for detecting the presence of ischemic heart disease was evaluated in 38 patients with coronary artery disease (group 1), 21 patients with chest pain and no coronary artery disease (group 2), and 33 healthy control subjects. The ventricular gradient of each consecutive heartbeat at rest over a 22-second interval was calculated using a microcomputer. The SD and coefficient of variation for azimuth, elevation, and magnitude were used as indices of ventricular gradient variability. The SD and coefficient of variation of both the magnitude and elevation of ventricular gradient in group 1 were significantly greater than those of the other two groups (P < .01, respectively). When the normal upper limit was defined as 2SD above the mean value in the control group, a comparison between the findings for group 1 and group 2 revealed that the coefficient of variation of magnitude of the ventricular gradient was the most sensitive (82%) and specific (91%) index for coronary artery disease (chi-square test, P < .001). This study suggests that the variability in the magnitude of the ventricular gradient is a reliable index of ischemic heart disease.
S Horinaka; H Yamamoto; T Tabuchi; M Takada; T Akabane; M Onoda; S Yagi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  28     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-11-28     Completed Date:  1995-11-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  177-83     Citation Subset:  IM    
Department of Medicine, Dokkyo University School of Medicine, Tochigi, Japan.
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MeSH Terms
Heart Ventricles / physiopathology*
Middle Aged
Myocardial Ischemia / diagnosis*,  physiopathology
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity

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