Document Detail

Ventricular fibrillation in a patient with 'silent' mitral valve prolapse.
MedLine Citation:
PMID:  3370657     Owner:  NLM     Status:  MEDLINE    
A patient with clinically silent mitral valve prolapse experienced an episode of out-of-hospital cardiac arrest due to ventricular fibrillation. This arrhythmia was easily replicated in the electrophysiology laboratory and despite treatment with amiodarone alone and amiodarone in combination with propranolol. Amiodarone in combination with quinidine prevented the induction of ventricular fibrillation and proved effective during a 3-year follow-up period. Even though a clear-cut relationship between the arrhythmias and mitral valve prolapse cannot be established, this case suggests that sudden death can occur in patients with mitral valve prolapse but without the known risk factors for the development of sudden death.
B Strasberg; A Caspi; J Kusniec; R F Lewin; S Sclarovsky; J Agmon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cardiology     Volume:  75     ISSN:  0008-6312     ISO Abbreviation:  Cardiology     Publication Date:  1988  
Date Detail:
Created Date:  1988-06-27     Completed Date:  1988-06-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1266406     Medline TA:  Cardiology     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  149-53     Citation Subset:  IM    
Electrophysiology Unit, Massada Center for Heart Diseases, Beilinson Medical Center, Petah Tikva, Israel.
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MeSH Terms
Amiodarone / therapeutic use
Death, Sudden / etiology
Drug Therapy, Combination
Follow-Up Studies
Heart Arrest / etiology*
Mitral Valve Prolapse / complications*,  diagnosis
Propranolol / therapeutic use
Quinidine / therapeutic use
Ventricular Fibrillation / complications*,  drug therapy
Reg. No./Substance:
1951-25-3/Amiodarone; 525-66-6/Propranolol; 56-54-2/Quinidine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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