Document Detail

Ventricular capture management in pediatric pacing: efficacy and safety.
MedLine Citation:
PMID:  16212078     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The Ventricular Capture Management (VCM) of Medtronic Kappa 700 series pacemakers (PM) performs automatic threshold detection and optimization of pacing output that may enhance generator longevity. We evaluated efficacy and safety of this algorithm in children. METHODS: The study was prospective, non-randomized, involving 50 consecutive patients (mean age 5.6 +/- 6.6 years, median 4 years), enrolled at first PM implant. VCM was active from the implant, with nominal values of safety margin, minimum adapted pulse amplitude and width. Leads were endocardial and epicardial, all unipolar. Thresholds and pacing outputs were registered with telemetric PM interrogation. Endocardial and epicardial thresholds and outputs were also compared. Follow-up duration was 27 +/- 13 months (range 6-49 months). RESULTS: A significant reduction in pulse amplitude was evident since the sixth month. Thresholds and outputs were lower in endocardial than in epicardial pacing. A false negative capture detection occurred during the "acute phase" in 3 patients (6.0%), with incorrect automatic output increase to 5 V/1 ms. After this phase, the problem was still detected in 2 patients (4.0%). VCM correctly identified threshold increases in 2 patients (1%). No pacing defect was documented. VCM was not performed in 4 infants (8.0%) for pacing rate > or = 100 b/min. CONCLUSIONS: VCM function is safe and effective in reducing pacing output in pediatric patients; this may increase PM longevity. Epicardial pacing shows higher thresholds and outputs than endocardial pacing.
Massimo S Silvetti; Antonella De Santis; Giorgia Grutter; Vincenzo Di Ciommo; Fabrizio Drago
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Italian heart journal : official journal of the Italian Federation of Cardiology     Volume:  6     ISSN:  1129-471X     ISO Abbreviation:  Ital Heart J     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-10-10     Completed Date:  2006-06-06     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100909716     Medline TA:  Ital Heart J     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  751-6     Citation Subset:  IM    
Cardiac Arrhythmias Service, Bambino Gesi Pediatric Hospital, Rome, Italy.
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MeSH Terms
Arrhythmias, Cardiac / physiopathology*,  therapy*
Cardiac Output
Cardiac Pacing, Artificial*
Child, Preschool
Equipment Design
Equipment Safety
Follow-Up Studies
Heart Conduction System / physiopathology,  surgery
Heart Ventricles / physiopathology,  surgery
Pacemaker, Artificial*
Prospective Studies
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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