| Ventricular assist device use with mechanical heart valves: an outcome series and literature review. | |
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MedLine Citation:
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PMID: 11789792 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Management of postcardiotomy cardiogenic shock with a ventricular assist device (VAD) is a common and accepted therapeutic option. However, VAD use in patients with mechanical heart valves (MHVs) is thought to carry an increased risk of thromboembolus. We report a series of 7 patients with combined VAD-MHV and review the literature. METHODS: A retrospective review was performed on all patients who were supported with a ventricular assist device with a mechanical heart valve in place. A literature review was also performed from 1966 to 2000. RESULTS: Seven patients were identified from April 1988 to June 2000 as having VAD support with a MHV. One thromboembolic event was documented in the 7 patients (14%). Five of the 7 patients (71%) underwent VAD explantation. Overall survival rate was 3 of 7 (43%). Causes of death included heart failure, renal failure, multisystem organ failure, adult respiratory distress syndrome, and cerebral hypoxia. All patients who died had support withdrawn at the request of the family. All patients discharged are currently alive with length of survival of 3, 26, and 84 months. CONCLUSIONS: This study suggests that this population's rate of survival to discharge and risk of thromboembolus compare favorably to that of the general VAD population. We believe that anticoagulation can be managed as with any MHV patient and that flow rates can be kept slightly lower, which may encourage valve washing. |
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Authors:
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W B Tisol; D K Mueller; F B Hoy; R C Gomez; B S Clemson; S M Hussain |
Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 72 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2001 Dec |
Date Detail:
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Created Date: 2002-01-14 Completed Date: 2002-01-31 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: United States |
Other Details:
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Languages: eng Pagination: 2051-4; discussion 2055 Citation Subset: AIM; IM |
Affiliation:
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Division of Cardiovascular and Thoracic Surgery, University of Illinois College of Medicine, Peoria, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Cause of Death Device Removal Female Follow-Up Studies Heart Valve Prosthesis* Heart-Assist Devices* Humans Male Middle Aged Postoperative Complications / etiology*, mortality Prosthesis Design Risk Factors Shock, Cardiogenic / mortality, surgery* Survival Analysis Thromboembolism / etiology* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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