| Ventricular function in surgery for congenital heart disease. | |
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MedLine Citation:
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PMID: 19921328 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND The history of measuring myocardial edema by two-dimensional echocardiography and the pathophysiology of myocardial edema are reviewed. METHODS The relevance of this subject to management of children undergoing corrective surgery for single ventricle physiology and tetralogy of Fallot is reviewed. RESULTS Evidence is presented that myocardial edema is an ongoing clinical problem with relevance to management and outcomes. Methods for measuring mass increases noninvasively in the range of 10-25% with increases in myocardial water content on the order of 2-4% are now well established. CONCLUSIONS These methods and advanced animal models replicating conditions of surgery for cyanotic congenital heart disease set the stage for clinical advances in this important area. |
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Authors:
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Henry M Spotnitz |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: World journal of surgery Volume: 34 ISSN: 1432-2323 ISO Abbreviation: World J Surg Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-16 Completed Date: 2010-06-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7704052 Medline TA: World J Surg Country: United States |
Other Details:
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Languages: eng Pagination: 669-74 Citation Subset: IM |
Affiliation:
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Department of Surgery, Columbia University Medical Center, Vanderbilt Clinic 1010, 622 W 168th Street, New York, NY 10032, USA. hms2@columbia.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cardiac Surgical Procedures / methods* Disease Models, Animal Echocardiography Edema / physiopathology, ultrasonography Fontan Procedure Heart Defects, Congenital / physiopathology, surgery*, ultrasonography Heart Ventricles / abnormalities*, surgery*, ultrasonography Humans Papio Swine Tetralogy of Fallot / physiopathology, surgery, ultrasonography Ventricular Dysfunction, Left / physiopathology, surgery*, ultrasonography |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL-48109/HL/NHLBI NIH HHS; R01HL-22894/HL/NHLBI NIH HHS; R01HL-41163/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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