Document Detail


Ventilatory pattern and chest wall mechanics during ketamine anesthesia in humans.
MedLine Citation:
PMID:  3777478     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of anesthetic doses of ketamine (iv bolus of 3 mg X kg-1 followed by a continuous infusion of 20 micrograms X kg-1 X min-1) on functional residual capacity (FRC) measured by the helium dilution method and on the breathing pattern recorded by a noninvasive method (NIM) based on chest wall circumference changes were studied in 14 ASA P.S. I patients. Ketamine anesthesia was associated with: 1) the maintenance of FRC, minute ventilation, and tidal volume; 2) an increase in rib cage contribution to tidal breathing; and 3) an alteration of volume-motion relationships of the chest wall compartments. It is concluded that: 1) in contrast to volatile anesthetic agents, ketamine anesthesia has a sparing effect on intercostal muscle activity, which may explain the maintenance of FRC; and 2) changes in chest wall geometry and compliance induced by anesthetic agents must be taken into account for NIM to be valid.
Authors:
B Mankikian; J P Cantineau; R Sartene; F Clergue; P Viars
Related Documents :
11964608 - Does the immobilizing effect of thiopental in brain exceed that of halothane?
23487438 - Relationships between vertical jump and full squat power outputs with sprint times in u...
3558218 - Quantification of thoracic volumes by three-dimensional imaging.
3354888 - Conscious state comparisons of the effects of the inhalation anesthetics and diltiazem,...
23960448 - Systematic review and meta-analysis of pulmonary hypertension specific therapy for exer...
6341338 - Effects of 0.1 ppm nitrogen dioxide on airways of normal and asthmatic subjects.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesiology     Volume:  65     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  1986 Nov 
Date Detail:
Created Date:  1986-11-28     Completed Date:  1986-11-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  492-9     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anesthesia, Intravenous*
Calibration
Functional Residual Capacity
Humans
Ketamine / pharmacology*
Lung Volume Measurements / standards
Male
Movement
Respiration / drug effects*
Respiratory Muscles / drug effects
Thorax / drug effects*,  physiology
Tidal Volume
Chemical
Reg. No./Substance:
6740-88-1/Ketamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A dopaminergic receptor in adrenal medulla as a possible site of action for the droperidol-evoked hy...
Next Document:  Edrophonium antagonizes combined lidocaine-pancuronium and verapamil-pancuronium neuromuscular block...