Document Detail

Ventilatory effects of inhaled capsaicin in man.
MedLine Citation:
PMID:  3556377     Owner:  NLM     Status:  MEDLINE    
Nebulised capsaicin (10(-7) M) was inhaled by 8 normal subjects to study its effects on the pattern of breathing. When compared to the diluent alone capsaicin increased mean inspiratory flow, a reflection of central inspiratory drive (mean increase: 25 +/- 6%, SEM, p less than 0.01), with a trend to increasing ventilation through more rapid but not more shallow breathing. If capsaicin selectively stimulates non-myelinated fibres in the lung in man as it does in dogs, these results suggest that such stimulation in man can alter the pattern of breathing.
D L Maxwell; R W Fuller; C M Dixon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of clinical pharmacology     Volume:  31     ISSN:  0031-6970     ISO Abbreviation:  Eur. J. Clin. Pharmacol.     Publication Date:  1987  
Date Detail:
Created Date:  1987-05-18     Completed Date:  1987-05-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1256165     Medline TA:  Eur J Clin Pharmacol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  715-7     Citation Subset:  IM    
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MeSH Terms
Bronchi / drug effects
Capsaicin / administration & dosage,  pharmacology*
Respiration / drug effects*
Respiratory Function Tests
Reg. No./Substance:
0/Aerosols; 404-86-4/Capsaicin

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