Document Detail


Ventilation practices in the neonatal intensive care unit: a cross-sectional study.
MedLine Citation:
PMID:  20619854     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess current ventilation practices in newborn infants. STUDY DESIGN: We conducted a 2-point cross-sectional study in 173 European neonatal intensive care units, including 535 infants (mean gestational age 28 weeks and birth weight 1024 g). Patient characteristics, ventilator settings, and measurements were collected bedside from endotracheally ventilated infants. RESULTS: A total of 457 (85%) patients were conventionally ventilated. Time cycled pressure-limited ventilation was used in 59% of these patients, most often combined with synchronized intermittent mandatory ventilation (51%). Newer conventional ventilation modes like volume targeted and pressure support ventilation were used in, respectively, 9% and 7% of the patients. The mean tidal volume, measured in 84% of the conventionally ventilated patients, was 5.7 ± 2.3 ml/kg. The mean positive end-expiratory pressure was 4.5 ± 1.1 cmH(2)O and rarely exceeded 7 cmH(2)O. CONCLUSIONS: Time cycled pressure-limited ventilation is the most commonly used mode in neonatal ventilation. Tidal volumes are usually targeted between 4 to 7 mL/kg and positive end-expiratory pressure between 4 to 6 cmH(2)O. Newer ventilation modes are only used in a minority of patients.
Authors:
Anton H van Kaam; Peter C Rimensberger; Dorine Borensztajn; Anne P De Jaegere;
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  157     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-19     Completed Date:  2010-11-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  767-71.e1-3     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 Mosby, Inc. All rights reserved.
Affiliation:
Department of Neonatology, Emma Children's Hospital, Academic Medical Center, Amsterdam, the Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Cross-Sectional Studies
Female
Humans
Infant, Newborn
Intensive Care Units, Neonatal
Male
Prospective Studies
Respiration, Artificial / methods*
Respiratory Insufficiency / therapy*
Investigator
Investigator/Affiliation:
A Debeer / ; A Chemin / ; K Norbert / ; F Autret / ; A Andreou / ; A Kroon / ; A Minić / ; J Schwindt / ; H Brouwers / ; P van Reempts / ; H Hummler / ; M van Veenendaal / ; K Sarafidis / ; E Lopriore / ; F Mosca / ; K McCormick / ; T Schaible / ; A Jaarsma / ; V Polimeni / ; R Plavka / ; L Pazderova / ; J Patkai / ; G Moriette / ; A Valls / ; I Soler / ; P Clarke / ; C Migliori / ; R Hentschel / ; J Sigalas / ; M Ehlen / ; C Fremerey / ; M Roujou-Gris / ; M Stamatin / ; Q Mok / ; S Ata / ; M Günther / ; J Kühr / ; U Seitz / ; M Vermeulen / ; R Knol / ; S Le Bouedec / ; D Szekessy / ; R Wauer / ; C Petropoulou / ; J Moreno Hernando / ; B Jonsson / ; T Mulder / ; D Sweet / ; E Herting / ; W Goepel / ; G Dimitriou / ; H Stuchlíkova / ; M Baltogianni / ; S Andronikou / ; V Santillo / ; F Ferrero / ; I Arnault / ; J Dort / ; T Blanc / ; G Rocha / ; H Guimarães / ; D Virella / ; A Costa / ; S Pedro Frutuoso / ; J Biolek / ; S Stoicescu / ; M Schroth / ; C Cirstoveanu / ; W de Boode / ; S Müller-Hansen / ; C Poets / ; T Riedel / ; K Palmer / ; C Martano / ; I Stucin Gantar / ; P Biban / ; S Chatfield / ; J Ghesquiere / ; B Theret / ; S Samperiz / ; T Berger / ; V Rigo / ; A Balato / ; M Gresa Munoz / ; A Nunes / ; H Molendijk / ; S Beuger / ; A Puzas / ; S Hiedl / ; O Genzel-Boroviczeny / ; D Anhalt / ; J Möller / ; F Ingemansson / ; F Halbertsma / ; V de Cesaris / ; T Saarela / ; P Karagianni / ; C Tsakalidis / ; P Tølløfsrud / ; A Bougatef / ; R Sindelar / ; K Wisborg / ; T Brink Henriksen / ; C Flumini / ; V Carnielli / ; S Giannuzzo / ; A Dussart / ; D Brault / ; M Samy / ; A van Wien / ; M Cunha / ; E Paulino / ; H Schneider / ; A Sandvoss / ; P Dahlem / ; B Koester / ; E Olhanger / ; R Wentzell / ; C Ramos / ; M Augusta Areias / ; I Verber / ; G Presta / ; R Magaldi / ; R Agostino / ; O Lund / ; J Ulriksen / ; D Faas / ; R Jensen / ; G Baroutis / ; V Gouder de Beauregard / ; G Zaharie / ; A Eng-Schwartz / ; M Heldmann / ; T Cezanne / ; A Pereira / ; M Nelle / ; F Uxa / ; M Norman / ; J Siegel / ; M Welsch / ; H Schiffmann / ; L Haftel / ; F Wild / ; P Bühr / ; B Simma / ; A Thirumurugan / ; S Mortensen / ; R Ciccotti / ; G Carli / ; D Milligan / ; H Gerleve / ; B Kumararatne / ; S Hakansson / ; D O'Donovan / ; F Reiterer / ; P Rimensberger / ; L Nietsch / ; B Nakstad / ; P Gancia / ; S Swanstrom / ; P Maton / ; E Cavatorta / ; R Tvarijonoviciene / ; M Hogan / ; P Zinn / ; M Freff / ; H Reigstad / ; G Olariu / ; G Gonçalves / ; M Escumalha / ; H Ornelas / ; A Serrano / ; S Anderssen / ; P Garcia / ; A Mendes Da Graça / ; C Bender / ; M Wald / ; M Bohn / ; A Schnelke / ; T Trips / ; J Ladekjaer / ; F Thompson / ; E Lindberg / ; M Frigerio / ; F Pederzini / ; G De Nisi / ; G Saur / ; M Losa / ; A Toma / ; E Matu / ; S Eckhardt / ; M Bellettato / ; H Fahnenstich / ; P Hetzel / ; J Bland / ; B Øglaend / ; L Lehtonen / ; T Eichler / ; M Roth / ; A Meberg / ; T Kuehn / ; M Emeis /

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