| Venous ulcers of the lower limbs due to congenital thalidomide-related valve defect. | |
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MedLine Citation:
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PMID: 17652228 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 44-year-old woman with fetal thalidomide syndrome and congenital pseudoainhum of the left big toe had a 5-year history of painful nonhealing ulcers in the left malleolar region. Venous Doppler ultrasonography showed hypoagenesis of the valve flaps of the deep and superficial venous circuit. To our knowledge, this is the first description of congenital pseudoainhum associated with fetal thalidomide syndrome. The coexistence of cutaneous ulcers in our case might be coincidental but may be related to a congenital valve defect (hypoagenesis) caused by thalidomide. |
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Authors:
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Pietro Rubegni; Sara Poggiali; Roberta Bilenchi; Agnese Diana; Massimiliano Risulo; Letizia Civeli; Michele Fimiani |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-07-24 |
Journal Detail:
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Title: Angiology Volume: 58 ISSN: 0003-3197 ISO Abbreviation: Angiology Publication Date: 2007 Aug-Sep |
Date Detail:
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Created Date: 2007-09-18 Completed Date: 2007-10-02 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0203706 Medline TA: Angiology Country: United States |
Other Details:
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Languages: eng Pagination: 491-3 Citation Subset: IM |
Affiliation:
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Section of Dermatology, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy. rubegni@unisi.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Heart Valve Diseases* / chemically induced, complications, congenital Humans Maternal Exposure / adverse effects* Teratogens Thalidomide / adverse effects* Ultrasonography, Doppler Varicose Ulcer / etiology*, ultrasonography |
| Chemical | |
Reg. No./Substance:
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0/Teratogens; 50-35-1/Thalidomide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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