Document Detail

Venous gangrene of the limb. Pathophysiological and therapeutic considerations.
MedLine Citation:
PMID:  1888117     Owner:  NLM     Status:  MEDLINE    
Venous gangrene of the limb is a rare disease. Peripheral arterial collapse has been shown to underlie the ischaemia. The two patients studied had venous gangrene and malignancy of the gastrointestinal tract with liver metastases. One patient had slowly and the other rapidly progressing gangrene despite heparin-warfarin therapy. Both patients died. Microscopy revealed occlusive thrombosis of small peripheral arteries of the leg. The authors conclude that the pathophysiology in venous gangrene may be occlusive thrombosis of small arteries. This situation is the lethal form of the entity and responds poorly to established therapy.
V Perhoniemi; R Kaaja; O Carpén
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annales chirurgiae et gynaecologiae     Volume:  80     ISSN:  0355-9521     ISO Abbreviation:  Ann Chir Gynaecol     Publication Date:  1991  
Date Detail:
Created Date:  1991-10-08     Completed Date:  1991-10-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7609767     Medline TA:  Ann Chir Gynaecol     Country:  FINLAND    
Other Details:
Languages:  eng     Pagination:  68-70     Citation Subset:  IM    
Department of Surgery, Maria City Hospital, Helsinki, Finland.
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MeSH Terms
Thrombophlebitis* / complications,  pathology,  physiopathology,  therapy

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