Document Detail


Venous flow restriction: the role of vein wall motion in venous admixture.
MedLine Citation:
PMID:  15234700     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: There are wide differences in flow between vascular beds at rest, even more during stress. The hydrodynamic energy (Energy grade line or EGL) of venous outflows must also vary considerably between vascular beds. We explored the mechanism of venous admixture of differing energy flows using a mechanical model. MATERIALS AND METHODS: The model simulated two venous flows coalescing at a venous junction and then flowing through collapsible venous pumps. Flow rates and pressures were monitored when the venous pumps were full (steady state) and when they were compressed and allowed to refill inducing wall motion (pump flow). RESULTS: With increasing EGL differences between two coalescing venous flows, reduction or cessation (venous flow restriction) of the weaker flow occurred during steady state; higher base EGL of both flows ameliorated venous flow restriction and lower base EGL the opposite. Outflow obstruction favoured venous flow restriction. Pump action in the vicinity of the venous junction abolished venous flow restriction and maximized both venous flows. CONCLUSION: The model suggests a pivotal role for vein wall motion in venous admixture and regional perfusion. Observations in the model are explained on the basis of network flow principles and collapsible tube mechanics.
Authors:
S Raju; G Cruse; M Berry; S Owen; E F Meydrech; P N Neglen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery     Volume:  28     ISSN:  1078-5884     ISO Abbreviation:  Eur J Vasc Endovasc Surg     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-05     Completed Date:  2004-08-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9512728     Medline TA:  Eur J Vasc Endovasc Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  182-92     Citation Subset:  IM    
Affiliation:
River Oaks Hospital and University of Mississippi Medical Center, Jackson, MS 39232, USA.
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MeSH Terms
Descriptor/Qualifier:
Biomechanics
Blood Pressure / physiology
Blood Vessels / physiology*
Humans
Models, Biological
Movement / physiology
Transducers
Vascular Resistance / physiology*

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