| Venous and cerebrospinal fluid flow in multiple sclerosis: a case-control study. | |
| | |
MedLine Citation:
|
PMID: 20695018 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The prevailing view on multiple sclerosis etiopathogenesis has been challenged by the suggested new entity chronic cerebrospinal venous insufficiency. To test this hypothesis, we studied 21 relapsing-remitting multiple sclerosis cases and 20 healthy controls with phase-contrast magnetic resonance imaging. In addition, in multiple sclerosis cases we performed contrast-enhanced magnetic resonance angiography. We found no differences regarding internal jugular venous outflow, aqueductal cerebrospinal fluid flow, or the presence of internal jugular blood reflux. Three of 21 cases had internal jugular vein stenoses. In conclusion, we found no evidence confirming the suggested vascular multiple sclerosis hypothesis. |
| | |
Authors:
|
Peter Sundström; Anders Wåhlin; Khalid Ambarki; Richard Birgander; Anders Eklund; Jan Malm |
Related Documents
:
|
12963748 - The utility of mri in suspected ms: report of the therapeutics and technology assessmen... 20663418 - Clinical usefulness of cerebrospinal fluid evaluation. 12708808 - Predicting multiple sclerosis at optic neuritis onset. 15742608 - Ankylosing spondylitis and multiple sclerosis in an hla-b27 negative patient. 21148258 - Fetuses with ventriculomegaly diagnosed in the second trimester of pregnancy by in uter... 9476948 - Marrow versus infection in the charcot joint: indium-111 leukocyte and technetium-99m s... |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Annals of neurology Volume: 68 ISSN: 1531-8249 ISO Abbreviation: Ann. Neurol. Publication Date: 2010 Aug |
Date Detail:
|
Created Date: 2010-08-09 Completed Date: 2010-10-14 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7707449 Medline TA: Ann Neurol Country: United States |
Other Details:
|
Languages: eng Pagination: 255-9 Citation Subset: IM |
Affiliation:
|
Department of Clinical Neuroscience, Umeå University, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Case-Control Studies Cerebral Veins / pathology, physiopathology Cerebrospinal Fluid / physiology* Female Humans Hyperemia / complications, pathology, physiopathology* Magnetic Resonance Angiography / methods Male Middle Aged Multiple Sclerosis / etiology, pathology, physiopathology* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Disrupted SOX10 regulation of GJC2 transcription causes Pelizaeus-Merzbacher-like disease.
Next Document: Mutations in PEX10 are a cause of autosomal recessive ataxia.