Document Detail


Venous Pulse Transit Time in Normal Pregnancy and Preeclampsia.
MedLine Citation:
PMID:  22378859     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Uncomplicated pregnancies (n = 16) were evaluated longitudinally and compared to early- (n = 12) and late-onset (n = 14) preeclampsia patients, assessed once at diagnosis. Pulse transit time (PTT), equivalent to pulse wave velocity, was measured as the time interval between corresponding characteristics of electrocardiography and Doppler waves, corrected for heart rate, at the level of renal interlobar veins, hepatic veins, and arcuate branches of uterine arteries. Impedance cardiography was used to measure PTT at the level of the thoracic aorta. In normal pregnancy, all PTT increased gradually (P ≤ .01). Pulse transit time was shorter in late-onset preeclampsia (P < .05) and also in early-onset preeclampsia, with exception for hepatic veins and thoracic aorta (P > .05). Our results indicate that PTT is an easy and highly accessible measure for vascular reactivity at both arterial and venous sites of the circulation. Our observations correlate well with known gestational cardiovascular adaptation mechanisms. This suggests that PTT could be used as a new parameter in the evaluation and prediction of preeclampsia.
Authors:
Kathleen Tomsin; Tinne Mesens; Geert Molenberghs; Wilfried Gyselaers
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-28
Journal Detail:
Title:  Reproductive sciences (Thousand Oaks, Calif.)     Volume:  -     ISSN:  1933-7205     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101291249     Medline TA:  Reprod Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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